Clinical, Medicolegal and Research Radiology
Dr Darren Boone MD MRCS FRCR
Consultant oncological and gastrointestinal radiologist
Consultant Lower GI and Oncological Radiologist
University College London Hospital NHS Foundation Trust
Honorary Research Associate
Division of Medicine, University College London
Prior consultant appointments
2011-2017 Consultant Gastrointestinal and General Radiologist
Colchester Hospital University NHS Foundation Trust, Essex
2014-2017 Visiting Senior Lecturer
Postgraduate Medical Institute, Anglia Ruskin University, Cambridge
Gastrointestinal Radiology Fellowship
2009-2011 MD (Research)
Centre for Medical Imaging, University College London
Radiology Specialist Training
2005-2009 University College Hospital, London
2002–2005 Colchester Hospital University Foundation Trust, Essex
House Officer Appointments
2002-2002 Surgery: St Peter’s Hospital, Chertsey, Surrey
2001-2002 Medicine: Frimley Park Hospital, Frimley, Surrey
2013 MD (Research) University College London
2009 FRCR Royal College of Radiologists, London
2005 MRCS Royal College of Surgeons, England
2001 MBBS (Distinction) St George’s Hospital Medical School, London
1998 BSc (II:I) Biomedical science, University of London
1995 A Level (4 grade A) Chemistry, mathematics, physics and biology
1993 GCSE (9 grade A) Colchester Royal Grammar School, Essex
Prizes and Awards
1997 Wolfson Foundation BSc Scholarship
1996 Anne Selina Ferneé Scholarship
Boone D, Plumb A, Taylor SA (2018). Chapter 22: The large bowel. In: Adam A, Dixon A, Gillard J, Schaefer-Prokop C, Grainger R (Eds), Grainger and Allison’s Diagnostic Radiology, 7th edition, New York, USA: Churchill Livingstone
Boone D, Halligan S, Taylor SA (2013). CTC Background and Development.
In: Cash, B. (Ed.), Colorectal Cancer Screening and Computerized Tomographic Colonography: A Comprehensive Overview (pp 41-58). New York, USA: Springer
Boone D, Taylor SA, Halligan S. (2013). Rectal cancer.
In: E. Neri, L. Faggioni, C. Bartolozzi.(Eds.), CT Colonography Atlas (pp 133-150). Berlin Heidelberg. Springer-Verlag
Invited Reviews and Editorials
Boone D, Taylor SA (2019).
Chapter 2: MR of the small bowel: How to do it.
In: Laghi A (Ed) MRI Clinics: MR Imaging of the Bowel. Philadelphia, USA: Elsevier
Boone D, Taylor SA, Halligan S.
Diffusion weighted MRI: Overview and implications for rectal cancer management.
Colorectal Dis. 2013 Jun;15(6):655-61
Boone D, Taylor SA, Halligan S.
Evidence Review and Status Update on Computed Tomography Colonography.
Curr Gastroenterol Rep. 2011;13(5):486-94
Peer Reviewed Conference Proceedings
Roth H, Boone D, Halligan S, Hampshire T, Slabaugh G, McQuillan J, et al. External Clinical Validation of Prone and Supine CT Colonography Registration, Abdominal Imaging. Computational and Clinical Applications, Lecture Notes in Computer Science, 7601, 10-19, Oct 2012.
Hampshire T, Roth H, Boone D, Slabaugh G, Halligan S, Hawkes D, Prone to Supine CT Colonography: Registration Using a Landmark and Intensity Composite Method, Abdominal Imaging. Computational and Clinical Applications, Lecture Notes in Computer Science, 7601, 1-9, Oct 2012.
Roth H, Hampshire T, McClelland J, Hu M, Boone D, Slabaugh G, Halligan S, Hawkes D, Inverse consistency error in the registration of prone and supine images in CT colonography, MICCAI Workshop on Computational and Clinical Applications in Abdominal Imaging 2011, Lecture Notes in Computer Science, 7029, 1-7, 2012.
Roth H, McClelland J, Modat M, Hampshire T, Boone D, Hu M, Ourselin S, Halligan S, Hawkes D, CT colonography: inverse-consistent symmetric registration of prone and supine inner colon surfaces, SPIE Medical Imaging 2013.
Hampshire T, Roth H, Hu M, Boone D, Slabaugh G, Punwani S, Halligan S, Hawkes D, Automatic prone to supine haustral fold matching in CT colonography using a Markov random field model, 14th International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI), Oct 2011.
Hampshire T, Roth H, Hu M, Boone D, Slabaugh G, Punwani S, et al. Automatic prone to supine haustral fold matching in CT colonography using a Markov random field model. Med Image Comput Comput Assist Interv. 2011;14(Pt 1):508-15.
Roth H, McClelland J, Modat M, Boone D, Hu MX, Ourselin S, et al. Establishing Spatial Correspondence between the Inner Colon Surfaces from Prone and Supine CT Colonography. Ed: Jiang T, Navab N, Pluim JPW, Viergever MA. Medical Image Computing and Computer-Assisted Intervention – MICCAI 2010, Pt Iii, 2010:497-504.
Roth H, McClelland J, Boone D, Hu M, Ourselin S, Slabaugh G, Halligan S, Hawkes D, Conformal Mapping of the Inner Colon Surface to a Cylinder for the Application of Prone to Supine Registration, 14th conference on Medical Image Understanding and Analysis (MIUA), Jul 2010.
Roth H, McClelland J, Modat M, Boone D, Hu M, et al. Establishing spatial correspondence between the inner colon surfaces from prone and supine CT colonography. Medical Image Computing and Computer-Assisted Intervention 2010; 497-504.
Peer Reviewed Original Articles
Aker M, Boone D, Chandramohan A, Leach J, Sizer B, Motson R, Arulampalam T
Diagnostic Accuracy of MRI in assessing Tumour Regression and Identifying Complete Response in Patients with Locally Advanced Rectal Cancer After Neoadjuvant Treatment Abdom Radiol (NY). 2018 May 16. doi: 10.1007/s00261-018-1627-8.
Halligan S, Boone D, Bhatnagar G, Ahmad T, Bloom S, Rodriguez-Justo M, Taylor
SA, Mallett S. Prognostic biomarkers to identify patients destined to develop
severe Crohn’s disease who may benefit from early biological therapy: protocol
for a systematic review, meta-analysis and external validation. Syst Rev. 2016
Dec 1;5(1):206. PubMed PMID: 27903285; PubMed Central PMCID: PMC5131410.
Jalil O, Afaq A, Ganeshan B, Patel UB, Boone D, Endozo R, Groves A, Sizer B,
Arulampalam T. Magnetic resonance-based texture parameters as potential imaging
biomarkers for predicting long term survival in locally advanced rectal cancer
treated by chemoradiotherapy. Colorectal Dis. 2017 Apr;19(4):349-362.
East JE, Saunders BP, Burling D, Tam E, Boone D, Halligan S, Taylor SA.
Mechanisms of hyoscine butylbromide to improve adenoma detection: A case-control
study of surface visualization at simulated colonoscope withdrawal. Endosc Int
Open. 2015 Dec;3(6):E636-41. doi: 10.1055/s-0034-1392771. PubMed PMID: 26716127;
PubMed Central PMCID: PMC4683134.
Plumb AA, Fanshawe TR, Phillips P, Mallett S, Taylor SA, Helbren E, Boone D,
Halligan S. Small Polyps at Endoluminal CT Colonography Are Often Seen But
Ignored by Radiologists. AJR Am J Roentgenol. 2015 Oct;205(4):W424-31.
Boone D, Mallett S, Mc Quillan J, Taylor SA, Altman DG, Halligan S.
Assessment of the incremental benefit of computer-aided detection (CAD) for interpretation of CT colonography by experienced and inexperienced readers. PLoS One. 2015 Sep 10;10(9):e0136624.
Helbren E, Fanshawe TR, Phillips P, Mallett S, Boone D, Gale A, Altman DG,
Taylor SA, Manning D, Halligan S. The effect of computer-aided detection markers
on visual search and reader performance during concurrent reading of CT
colonography. Eur Radiol. 2015 Jun;25(6):1570-8. doi: 10.1007/s00330-014-3569-z.
PubMed PMID: 25577518.
Mallett S, Phillips P, Fanshawe TR, Helbren E, Boone D, Gale A, Taylor SA,
Manning D, Altman DG, Halligan S. Tracking Eye Gaze during Interpretation of
Endoluminal Three-dimensional CT Colonography: Visual Perception of Experienced
and Inexperienced Readers. Radiology. 2014 Jul 15:132896.
Plumb A, Boone D, Fitzke H, Helbren E, Mallett S. Detection of extracolonic pathology by CTC colonography: A discrete choice experiment of perceived benefits versus harms. Radiology. 2014 May 22:131678.
Ghanouni A, Halligan S, Taylor SA, Boone D, Plumb A, Stoffel S, Morris S, Yao
GL, Zhu S, Lilford R, Wardle J, von Wagner C. Quantifying public preferences for
different bowel preparation options prior to screening CT colonography: a
discrete choice experiment. BMJ Open. 2014 Apr 3;4(4)
Ghanouni A, Halligan S, Plumb AO, Boone D, Wardle J, von Wagner C. Non- or full-laxative CT colonography vs. endoscopic tests for colorectal cancer screening: A randomised survey comparing public perceptions and intentions to undergo testing. Eur Radiol. 2014 Jul;24(7):1477-86.
Helbren E, Halligan S, Phillips P, Boone D, Fanshawe T, Taylor SA, Manning D, Gale A, Altman DG, Mallett S. Towards a framework for analysis of eye-tracking studies in the 3D environment: A study of visual search by experienced readers of endoluminal CT Colonography. Br J Radiol. 2014 May;87(1037):20130614. doi: 10.1259/bjr.20130614.
Boone D, Mallett S, Zhu S, Yao G, Bell N, Ghanouni A, von Wagner C, et al. Patients’ & Healthcare Professionals’ Values Regarding True- & False-Positive Diagnosis when Colorectal Cancer Screening by CT Colonography: Discrete Choice Experiment. 2013 Dec PLoS ONE. 2013 Dec. doi:10.1371/journal.pone.0080767
Ghanouni A, Halligan S, Taylor SA, Boone D, Plumb A, Wardle J, von Wagner C.
Evaluating patients’ preferences for type of bowel preparation prior to screening
CT colonography: convenience and comfort versus sensitivity and specificity. Clin
Radiol. 2013 Nov;68(11):1140-5.
Ghanouni A, Smith SG, Halligan S, Plumb A, Boone D, Yao GL, Zhu S, Lilford R,
Wardle J, von Wagner C. Public preferences for colorectal cancer screening tests:
a review of conjoint analysis studies. Expert Rev Med Devices. 2013 Jul;10(4):489-99
Hampshire T, Roth HR, Helbren E, Plumb A, Boone D, Slabaugh G, Halligan S,
Hawkes DJ. Endoluminal surface registration for CT colonography using haustral
fold matching. Med Image Anal. 2013 Dec;17(8):946-58.
Boone DJ, Halligan S, Roth HR, Hampshire TE, Helbren E, Slabaugh GG, McQuillan
J, McClelland JR, Hu M, Punwani S, Taylor SA, Hawkes DJ. CT colonography:
external clinical validation of an algorithm for computer-assisted prone and
supine registration. Radiology. 2013 Sep;268(3):752-60.
Phillips P, Boone D, Mallett S, Taylor SA, Altman DG, Manning D, Gale A,
Halligan S. Method for tracking eye gaze during interpretation of endoluminal 3D
CT colonography: technical description and proposed metrics for analysis.
Radiology. 2013 Jun;267(3):924-31.
Ghanouni A, Smith SG, Halligan S, Taylor SA, Plumb A, Boone D, von Wagner C.
An interview study analysing patients’ experiences and perceptions of
non-laxative or full-laxative preparation with faecal tagging prior to CT
colonography. Clin Radiol. 2013 May;68(5):472-8.
Ghanouni A, Smith SG, Halligan S, Plumb A, Boone D, Magee MS, Wardle J, von
Wagner C. Public perceptions and preferences for CT colonography or colonoscopy
in colorectal cancer screening. Patient Educ Couns. 2012 Oct;89(1):116-21. doi:
10.1016/j.pec.2012.05.007. Epub 2012 Jun 16.
Hampshire T, Roth H, Hu M, Boone D, Slabaugh G, Punwani S, Halligan S, Hawkes
D. Automatic prone to supine haustral fold matching in CT colonography using a
Markov random field model. Med Image Comput Assist Interv. 2011;14(Pt1):508-15.
Boone D, Halligan S, Mallett S, Taylor SA, Altman DG. Systematic review: bias
in imaging studies – the effect of manipulating clinical context, recall bias and
reporting intensity. Eur Radiol. 2012 Mar;22(3):495-505.
Roth HR, McClelland JR, Boone DJ, Modat M, Cardoso MJ, Hampshire TE, Hu M,
Punwani S, Ourselin S, Slabaugh GG, Halligan S, Hawkes DJ. Registration of the
endoluminal surfaces of the colon derived from prone and supine CT colonography.
Med Phys. 2011 Jun;38(6):3077-89.
Boone D, Halligan S, Frost R, Kay C, Laghi A, Lefere P, Neri E, Stoker J,
Taylor SA. CT colonography: who attends training? A survey of participants at
educational workshops. Clin Radiol. 2011 Jun;66(6):510-6.
Roth H, McClelland J, Modat M, Boone D, Hu M, Ourselin S, Slabaugh G,
Halligan S, Hawkes D. Establishing spatial correspondence between the inner colon
surfaces from prone and supine CT colonography. Med Image Comput Comput Assist
Interv. 2010;13(Pt 3):497-504.
Taylor SA, Robinson C, Boone D, Honeyfield L, Halligan S. Polyp
characteristics correctly annotated by computer-aided detection software but
ignored by reporting radiologists during CT colonography. Radiology. 2009
East JE, Saunders BP, Boone D, Burling D, Halligan S, Taylor SA. Uni- and
bidirectional wide angle CT colonography: effect on missed areas, surface
visualization, viewing time and polyp conspicuity. Eur Radiol. 2008
East JE, Saunders BP, Burling D, Boone D, Halligan S, Taylor SA. Surface
visualization at CT colonography simulated colonoscopy: effect of varying field
of view and retrograde view. Am J Gastroenterol. 2007 Nov;102(11):2529-35.
East JE, Saunders BP, Boone D, Halligan S, Taylor SA. Comprehensive mucosal
visualization at optical colonoscopy: Technique remains the key.
Gastroenterology. 2006 Sep;131(3):975-6.
I have published numerous abstracts related to the research described above – details available on request
I have presented the published and abstracted research described above extensively at local, national and international levels.
I was awarded the ‘Top 20 presenter’ at the European Society of Gastrointestinal and Abdominal Radiology (ESGAR) Conference in 2010 and 2011.
Since then, I have delivered invited lectures and conducted hands-on CT colonography training symposia every year.
I have recently chaired a session on future directions in gastrointestinal radiology at this year’s British Institute of Radiology Annual Congress and joined the Faculty at the 2019 European Society of Gastrointestinal and Abdominal Radiology postgraduate course.
As a member of the European Society of Gastrointestinal and Abdominal Radiology Educational Faculty I am comfortable with a broad range of training from individual supervision up to invited lectures for an international audience.
I have instructed at European CT colonography educational workshops for over eight years. Responsibilities have range from hands-on workshops to large group seminars
I designed, developed and implemented an interactive multimedia symposium on behalf of the ESGAR CT colonography training faculty. Presented at IMAGINE exhibitions at the European Congress of Radiology, 2008 and 2009.
I was invited to lecture at the European Congress of Radiology (ECR), European Society of Gastroenterological and Abdominal Radiology (ESGAR), the Joint Meeting of the European Society of Thoracic Imaging (ESTI) and the Fleischer Society in 2015
I have presented my research extensively on the subject of GI radiology with my outcomes informing practice at local, national and international levels.
Having been appointed as Royal College of Radiologists’ Speciality Tutor in 2014 to oversee training of all radiology postgraduate trainees within the Colchester training scheme I carried out a complete revision of the training programme, appointed a new educational faculty and saw our GMC survey result improve significantly.
I am currently an Educational Supervisor for the UCLH training scheme
In addition to radiology trainees, I regularly teach medical students, surgical registrars and foundation programme trainees. I have mentored several radiographers through their PgD in Clinical Reporting.
2017 – 2020 Clinical lead for CT, UCLH
2016 – 2017 Transformation team working group, Colchester and Ipswich
2014 – 2017 Royal College of Radiologists College Tutor, Essex, Beds and Herts
2011 – 2017 Bowel Cancer Screening Programme local quality assurance lead
2011 – 2017 CT colonography lead, Colchester Hospital
I was quality assurance lead for colorectal cancer imaging in Colchester for six years developing and maintaining a comprehensive audit of all CT colonography examinations performed both locally and at satellite NHS Bowel Cancer Screening Programme centres. I remain closely involved with the BCSP in my current role as an accredited CTC radiologist, teaching on international courses.
I have been providing expert witness medico-legal reports for over six years. I have undergone several relevant training courses and am currently in the process of obtaining the Bond Solon Cardiff University Certificate for Expert Witnesses in civil claims.
I have produced over 50 reports for The Court dealing with alleged negligence, instructed by both Claimant and Defendant solicitors. Currently, my work is split approximately equally with a ratio of 45:50:5 for defendant, claimant and single joint witness instructions respectively. The majority have been full liability (breach and causation) reports although I have also provided several ‘short’ screening reports where instructed.
I take great pride in my medicolegal work and despite full-time clinical commitments, I turn around all reports within less than six weeks and aim to address clarifications such as responses to Part 35 questions within one week. As a result, I have received excellent feedback from my instructing solicitors and their clients (available on request).
Interests and activities
Whilst at medical school I spent two years as entertainment manager where I was responsible for a complete revision of the light and sound systems in the student bar. By playing regular DJ sessions I ultimately gained the opportunity to play music at several London clubs. I continue to mix in my spare time and am trying to pass my (limited) skills onto my teenage children.
I try to spend as much of my spare time as I can with my young family. When I need to unwind, I have a classic mini that I am (still) in the process of restoring.
In the past I played chess for England having been British under 14 champion; I coached my local primary school team and saw the team qualify for the national finals.
Email PA email@example.com
Email direct firstname.lastname@example.org
Date of Birth 21/8/1977
GMC No 6031326
Professor Steve Halligan
Professor of Gastrointestinal Radiology
Centre for Medical Imaging
University College London
Dr Samantha Read
Divisional Clinical Director
University College Hospitals London
Professor Stuart Taylor
Professor of Gastrointestinal Radiology
Centre for Medical Imaging
University College London
Contact details available on request
Please contact Dr Boone using the form below. While we take every effort to safeguard your information, please do not include any personal or sensitive information. For matters of a confidential nature please contact our office on the number below.
+44 7742 03 02 05
New Town House